A good while ago, scientists made mice real muscular by modifying their genes. These same scientists have now developed an agent which does the job yet more effeciently:
The Johns Hopkins scientists who first created “mighty mice” have developed an agent that’s even more effective at increasing muscle mass in mice, by knocking out the gene that codes for myostatin.
Just two weekly injections of the new ACVR2B agent triggered a 60 percent increase in muscle size.
The researchers’ expectation is that blocking myostatin might help maintain critical muscle strength in people whose muscles are wasting due to diseases like muscular dystrophy or side effects from cancer treatment or AIDS.
It doesn’t take a genius to figure out we’ll be using it in the future to enhance the non-sick too. Maybe not with permanent genetic modifications right away. But that’s okay, because genetic modifications can be mimicked with the use of drugs.
We’re looking at a future here where everybody will be slim, muscular, hairy (on top), healthy and other things that we all crave for but can’t have due to our birth-given genetics.
For example, take a look at what other type of benefits you can have with a little bit of genetic tweaking:
We have little software programs inside us called genes, about 23 thousand of them. They were designed or evolved tens of thousands of years ago when conditions were quite different. I’ll give you just one example. The fat insulin receptor gene says, “Hold on to every calorie because the next hunting season may not work out so well.” And that’s a gene we’d like to reprogram. It made sense 20 thousand years ago when calories were few and far between. What would happen if we blocked that? We have a new technology that can turn genes off called RNA interference. So when that gene was turned off in mice, these mice ate ravenously and yet they remained slim. They got the health benefits of being slim. They didn’t get diabetes, didn’t get heart disease or cancer. They lived 20 to 25 percent longer while eating ravenously. There are several pharmaceutical companies who have noticed that might be a good human drug.
Earlier, Ellen Heber-Katz came up with super-regenerative mice, who can regrow limbs and organs.
Right now, these sort of things are research projects confined to laboratories.
We can expect these types of body upgrades to become mainstream in the biotech era, which is slated to be from 2010-2020.